Despite qualifying for armed force, Karthik ('Jayam ' Ravi) prefers to be a traffic cop in Ooty as he believes that such a no risky job would help him get enough time to look after his cute little sister Vidhya (Baby Anikha). Karthik also has a short lived one side love story with Renu (Lakshmi Menon), who is a doctor. When a hazardous chemical in the nearby industry gets leaked, a dog consumes it and turns into a zombie. As the dog bites a watchman, he too becomes a zombie and eventually, the virus spreads rapidly across the town. Can Karthik save his sister and the city ?

　　U Turn is a Mystery Thriller. A young female reporter is upset about how people break traffic rules, she wants to do a story about it and have it published. In this pursuit she finds herself struck in a police case dealing with series of murders. The film is about how she tries to free herself of these accusations and also becomes part of the investigation process. The rest of the film is about the mysterious deaths and how they are all interconnected with a road accident.

　　薇迪雅是单位的员工,和下半身不能动弹的女儿米妮相依为命,想有一天带着女儿去美国治疗.有一天,女儿不见了,绑匪要她去一个地方.就在她急忙忙赶去的时候,遭遇了车祸.因德尔吉特·辛格副督察接手了这起车祸案,他翻看了薇迪雅的日记,发现原来米妮并不是她女儿.原来8年前,米妮叔叔猥亵她,而薇迪雅最终把米妮救了出来,期间米妮奶奶被薇迪雅推倒在地身亡.薇迪雅也带着米妮逃离了,可遭到了警方的通缉.而现今的绑匪正是米妮的叔叔.其实,薇迪雅原来是因德尔吉特·辛格的前妻杜尔迦·拉妮·辛格......